Nice idea and good execution.
I think, there are a few problems with usability (pressing E to talk with people isn't shown as option, not being able to throw away stuff from the inventory, etc), but I still got the cure in my second try. I don't know if the loot is random, but I had the rare medicine ready in 2 days with only talking to 3 people, half of the map still covered in fog. So it kinda went against the theme of connection because nobody connected :D
But I think the idea has potential and it was fun to play :)