It could be a permissions error, basically the game crashing when it tries to save a change to it's own settings file. Is the game in your applications folder? If not, try moving it there and then running. If that doesn't work, you may also need to adjust the permissions for the game manually. Lastly, you could try updating the nw.js files for the game. You can get the latest mac files here: https://nwjs.io/downloads/ Then you just unzip them, and copy the "Contents" folder in the nwjs update into the "Game.app" folder in your game, overwriting existing files if prompted.
RPG Maker MV support for Mac ended some time ago, but the game sometimes works anyways. I just have no way to really tell when or why, so I just have to give my best guesses for what could fix it for you. If none of that works, you may need to either emulate the windows version or run the web version instead.