Hmm. Been playing the slightly-better-bugfixed build, and this glitch has killed my run twice: just barely doing the minigame to retort to the boss banter causes the DDR-input window to very slowly judder to the bottom of the screen, making a buzzing sound as it does. The buzzing continues after it leaves the screen. No input or behaviors other than idle animations happen after that, and the second time it happened, it was on the final boss (who I deliberately lost to so I could see the comeback line).
Viewing post in The Journey of Perla - Wings of Cuauhtli comments
Another bug report: falling to your death while having a potion - at least during the wind boss fight - fails to trigger the 'respawn on platform' code properly; it appears that Perla winds up under the screen somehow and can move the camera one screen right - or be moved, by the hurricane thing, which immediately moves her back so long as it's going. The lightning beam sometimes shows up there too. Can't open the pause menu, either. I expect this playthrough would be continuable if I could simply get Perla into a lethal hazard, but it's not working, and I can't seem to get hit by the one petrifying arrow the boss shoots straight downward; I'll likely have to reset again.
(I think, though it was a long time ago, that being petrified while falling to your death also breaks the game. That was the first time I played, and I was fireball-reflecting in order to sequence break to the wind area instead of going down the very long corridor with no save points to get the charge shot and dash.)