Well, that turned out to be pretty easy to recreate and also pretty easy to fix... it turns out i just, completely forgot to disable the ui during the little fade to black before loading your file, so when you were spamming enter it ended up loading up the game multiple times with multiple copies of everything, which lead to all the weirdness you're describing. Really embarrassing mistake, should be fixed for postjam though -.-
I still don't understand how this ended up bricking your file though - the game is supposed to just ignore corrupt files and plop you into a new save if one fails to load. Could you try opening the console and seeing what kind of error its putting out when you try to load it?