In theory yes. They made actual game cartridges i believe forthis game as an option for early backers. the game is built within the limitation of the nes and the rom works with nes emulators. I played it on an nes emulator on my psp in fact and it works great
Physical release is still for sale if you want one:
https://www.brokestudio.fr/product/micro-mages/
A Famicom version for your Famicom or Dendy is also about to be released.