The art is amazing! I do think there's issues with the rendering of textures where some of them have bilinear filtering and others are nearest. There's also "mixels" which is where some textures/objects have different resolutions and sizes to others, because it isn't on a defined pixel grid.
I think this game would have been WAYYY easier to make in Godot. Just my opinion. Godot is so much better for making 2d pixel art games (see mine hehe).
I think the lack of player feedback and "juice" (satisfying effects) makes this hard to play without getting bored.
The potion mechanics are awesome and the upgrade tree is a fantastic addition as well.
I have no idea if I have selected something in my inventory or not (no highlight on the selected tile). Makes it a bit annoying.
Great work! If this is your first game you did an AMAZING job. Audio/music would have been nice.
Good luck on your gamedev journey! Love your work so far <3