This feels like one of those niche games you stumble upon one day that at first glance seems like any other game but the more you play the more intrigued you are, the stranger everything seems and the more you want to know. I just finished the content available in the game right now after playing it over two days and god?????? I'm so fascinated???? What is going ON?????
And it's incredible because you can really tell just how much passion has gone into this project, there's so much to discover and the story isn't just some little thing added to give the game some context, it's the driving force behind the whole thing and it's done in such a way that really really builds the intrigue without giving away too much too quickly- and now I'm so desperate to know more!!!!!!!!!!!!!! From what I gather so far: [SPOILERS]
The Eden universe was collapsing somehow, and people tried to escape with their first attempt at space travel to another universe through dark matter, and only 3 was it? Ships survived? And there's some kind of issue that the people of Eden are suffering from, that these doctors came in to fix (doctors who live for a very very long time- a whole century in primary??? And then ANOTHER IN HIGHSCHOOL???? Dear lord that's the most horrific part of this entire story to be honest). I suspect it was some sort of gene splicing? To give people physical boosts or perhaps improve their genetic health (like how IRL scientists managed to splice genes from an extinct stoat(?) into the surviving modern ones to help boost the health of the otherwise very genetically limited breeding group, freaking awesome!!!), but clearly something went violently wrong. Some kind of Being, that wanted something and helped them but didn't say what it wanted as its part of the deal, and it did...something? And now everyone is stuck as mutants without seeming to know why, and we have these little echos of the patients that sort of look like microbes but could be glitched forms of hybrids, it's hard to visually tell (love that btw, leaves a lot to interpretation, one of the many benefits to pixel art in horroresque media :D). And Sirok apparently wasn't herself when she landed? Most interesting!! She also keeps mentioning 'swapping' and something else speaking through her, and other other self? Very curious..
I strongly suspect the Being to be the purple mist thing, as shown on the title screen and also the strange purple orbs with the tentacles that give you upgrades (pretty spooky how you have no choice but to accept the improvement...I get the vibe this is akin to what happened to the patients...), and the voice that keeps talking to us.
GOD there's just so much going on and I'm so fascinated!!!!!!!!!!!!!!!!!!!!!!!
OH also before I forget, I have encountered some bugs >.< The biggest one is most of the icons for the mutations is just a blank white square. 
This also means that the purple orb buff mostly just cycles through white squares with the occasional actual image- meaning I don't actually know what buff I'm getting most of the time >.< It also makes it hard to know what I'm upgrading in the abilities menu!
Also the image for the mega fiends is also a blank white square (same with the attack sprite I think?) . I've had a minor bug where (movable) white circles are left on the map after using the Psionic Beam OR the mega fiends, not sure which it was I don't fully remember >.< Didn't think to grab a screenshot, will do if I get it again!!
I've managed to get into the Furgrowth building but the boss fight doesn't seem to work properly. First time was as Baron and it took while of clicking and walking trying to figure out how to get in (door was open but I wasn't getting in) before suddenly I was just in and I have no idea what did it- anyway did the fight (without any of my buffs from the run seemingly- I was ungodly slow) and the boss dealt damage but after I hit 0 I didn't die. I killed it and nothing happened and I had to reload >.<
Second time was in Furgrowth again with Cielo using the dash ability, killed it (didn't hit 0 health this time so idk if that bug persisted), but again nothing happened and I had to reload.
Haven't yet tried the buildings on the other maps!!
Also occasionally an enemy will spawn and just not move, I saw this happen the most on the Ren'Boon map with the middle-sized blue acid lizards. Can still kill em tho!
Another time on the Ren'Boon map enemies just stopped dying o.o I was still taking damage but they just decided not to lmao- reloaded and that fixed it tho :D
For QOL updates, I love the variety of choice with the mutations but it is a PAIN having to reselect them every single time you wanna do another run >.< If it could automatically keep your selection, or perhaps have a new button that says like "Re-select last used mutations" and it just selects all mutations form your last run, that would be SOOOOOO helpful!!!!
Also would be good to have the map selection part be more obviously about maps jkdshgkjf- took me a hot minute to figure that out when first playing!! It could be like
"LOCATION:
<Furgrowth/Duin/Ren'Boon>"
For balancing, the Duin map as Sirok is REALLY hard, she is incredibly slow (which nullifies the supposed 'agile' part of her playstyle sjdhfksg), and the way there's a blindspot right in front of her where you can't damage enemies makes it very hard to fight. It is possible to overcome by staying on the run until you finally get (almost all) the speed buffs and can manoeuvre properly, but even with all her abilities unlocked and all upgrades bought (for everything) playing as her is just. Difficult? Much moreso than any of the others :0 Even once you have all the mutations done on that run it's still so easy to suddenly die, especially since you still take damage when doing the spin attack which requires getting up close >.<
Playing as Cielo on Ran'Boon is really fun cuz it's preeeeetty easy tbh but for the sake of balancing I feel as though I should mention it >w< It's fun especially after the kinda slog of Sirok's part, but once you have all the buffs it's kinda just too easy, just zip around the map killing groups and that's it until you beat the map which does feel comparatively unbalanced. I'd say it's good to have him stronger than the previous to give a sense of progression and reward for your work!! But maybe not quite that easy sdjhfkdjsg (though it's so fun so idk I'm torn lmao)
I'd also say to make the initial speed on all characters a bit higher, it does work to have em slower and build up your speed as you 'earn' it by collecting the souls, but tbh it's a bit tooooo slow imo? Especially when revisiting and doing another run late-game, even with all the speed upgrades it's still sososososo slow when starting a run o.o I wouldn't say to make em that much faster but just a bit could be good :D (Or mayhaps have the speed upgrade do more? Idk!!)
Of course this is all just my personal opinion as a random player, not a dev, in the end I have no idea what or how much you have planned!!! Either way I really enjoyed this game, I think it's a real hidden gem with a story like this, I can tell it's a real labour of love and honestly? That's my favourite kind of game :DDD Triple AAA graphics are nice and all but a lot of those games feel shallow, stuff like this is like kinda what indie game-making is about imo!! Having a Vision that you want to bring to fruition and I can really tell there's such a rich story waiting to be uncovered <3 Excellent work!!!!!