I think the UI effects can become too overwhelming. Especially when you got like 50 drones and every click produces 20 animated lines it quickly becomes more of a visual noise which runs at <1FPS. I think the game would benefit from a different display of loot.
Also the cargo scan is quite slow when you are scanning like 15k items. I think your creation of so many UI elements in that scroll panel is adding to the slow down a lot, but I'm not sure these UI elements are all that necessary. I think most people won't be interested in seeing the details of the cargo scan item Nr. 8629.
Example image of the busy UI after a few clicks:
