I guarantee you there are replication workflows using the room save method, which results in quests not triggering correctly and CGs not loading.
It will never get resolved though because it is not an intended play style.
It is not recommended at all if you want to see everything the game has to offer. But as you mention you can do so at your own risk.
It needs to be highlighted though, if you do this the developer or mods are not going to assist you in the mess you create 😅