I totally forgot about shotguns. There doesn't seem (to me) to be any item that would really seal the deal on them, even with minor buffs.
For cannons, I *think* that if you got that 3x Damage cannon with 3 of those cannon-buff items (and 24 heal, 24 shield), you could probably survive. Unfortunately, any other cannon wasn't good enough for me to beat the final bosses (that you can't avoid).
I'm really surprised about the buzzsaw! I wonder if you had built up a ton of health. I tried swapping the buzzsaw into a melee build, and I just found that it took up too much space. I found I dealt more damage without it than with it.
OK so I spent a few days and RNG was like
>0 grenade launchers total, like at all
>get 3 decent levelled grenades in one run but again, 0 launchers
FINALLY got a 50/50 melee/ranged win with a really simple setup but I honestly just couldn't get the RNG rolls needed to collect it for the past weeks somehow?
It really feels like melee wins are easier by simple RNG/item drop ratio. I really wanted AP bullet set for my SMGs but couldn't roll a single one in this run.
re. Buzzsaw (actually had like 3 wins with it lol) yeah had to get more health, and with daggers and the +damage/+health engine it works. Barely but does.

Re:Buzzsaw
1. Impressive. I never managed it.
2. Buzzsaw still feels broken, because from what I've seen two daggers (which you get really early in the game) is 100% always better than buzzsaw. By the time buzzsaw is running as fast as 2 daggers,, you could have been dealing 100dmg/s with daggers.
I actually did get the RNG for grenade launcher: 2 upgraded grenades, and grenade launcher. But guess what! That takes up 7 vertical slots, leaving just 1 more slot for other useful stuff. 100 damage every 8(?) seconds isn't that great for taking up the space of 4 weapons. 4 upgraded daggers (with no other melee buffs) deal almost exactly that amount of damage.
Buzzsaw, yes it is, daggers top it easily in terms of acquisition and upgrades (also I think I had those and the buzzsaw at same time)
Honestly upgraded thin dagger (and if you can get and upgrade - double-dagger) are just OP which makes ranged weapons feel useless by comparison.
Launcher - gonna stop trying for it and try the twin flamers thing now, but with how slow flame weapons are I don't feel its gonna work.