Thank you for your question!
Some antivirus programs may flag large .exe files simply because of their size or the way they're packed — this is a common false positive for indie games.
If you're downloading the game directly from the official page here on Itch.io, you can trust the file. Itch.io moderators do their best to keep the platform clean and regularly check for malicious content. I can assure you that the game doesn't contain any malware.
Let me know if you have any concerns — I'm happy to help!