> fatigue could also affect regular draw
I hesitated on this before, but just now I've changed fatigue to affect start-of-turn card draw as well. This happens after the fatigue reduction, so you have to accumulate 20+ fatigue to draw 1 less card at the start of turn.
In your example (if played with the new ascension on) it will completely stop card draw at about turn 40, which is I think an acceptable balance point.