I like the idea a lot, and I can see a lot of potential in something like this, but I feel like it's too easy.
The ability to move Grumpy Carlson around is detrimental, I think. It makes it easy to solve things. I think it would be funny if he was so grumpy, he won't move.
I love the little lore bits in the game, I really enjoyed that about it. It gives more depth to the silly little game, and it's just fun seeing how these characters relate to each other.
I think, instead of having the aliens all automatically fill space, maybe having the player actually have to select where each one goes would make it more stimulating. Perhaps holding down the mouse button and dragging will place aliens in whichever tile your mouse drags over. I think that'll keep it from being tedious.
I love the art style, it's super charming and fun.
Overall, love it, I just wish it was harder. Also, is the name a reference to Alien Isolation? If so, that's hilarious.