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Backup your saves.

On Windows the saves are stored separately, reinstall does not destroy the saves. Unless you go to C:\Users<User>\AppData\Roaming\RenPy\Harem Hotel and remove the save files there.

So you can do what developer suggested.

To be extra sure, you can do what haremguy suggested and copy the save files to a backup device.

Reinstalling the game will not effect your saves. Your saves are stored in %appdata%, so you could completely delete HH off your computer and still have those saves. Your saves will always load on new versions as well.