It's up to you! Whatever game engine you are most comfortable with is a fine choice!
I'm personally a fan of GameMaker: Studio. It's a pretty powerful engine for quick and dirty prototyping!
I'll probably be using Fusion 2.5 then
Alrighty! Have fun! :D
can I make a game with pixel art graphics drawn with ms paint?
Sure! As long as you use paint or a paint like program, any art style is fine! :D
