If the game supports scaling, enabling the fullscreen button in the itch settings would make the game easier to play.
Viewing post in Pathogenos jam comments
What you can do for future jams is in Godot project settings, change the Display->Window->Stretch->Mode to “Viewport” and Aspect to “keep”. Then, the fullscreen button on itch should always just make the existing view of the game bigger and you don’t need to think about it. But, I highly recommend playing around with those settings and learning what they do! image.png