Im also having a problem with the MtF. The estrogen at a point just stops progressing and it seems to fluctuate in the high 90s, which makes it impossible to achieve the bonus.
Viewing post in Ultimate Sissy Simulator comments
Answered that in this post: https://itch.io/post/12134345 The fix will most likely be part of alpha 3, as that is my primary focus right now. Thanks.