Hi, thanks for the comment. Accessibility wasn't a consideration when I first made this, so I'm glad to see that it works for the most part. I've been working on getting my sites and games accessible for screen readers lately, I will definitely look into converting those boxes over to text.
http://docs.buddywagner.com/games/InfiniCrawl/ there is no index file there, so it'll allow you to view the directory right click on the html file and save it. It's a single file, everything is self contained. :) But you won't get updates on your offline version.For achievements do you mean just within the game or tied to some achievement system somewhere?
For drugs, there are a few things in game that give you effects like that, the Ubertrank and Magic Berry. There is also a Deck of Fate that you can draw from to give you random effects. I could add more, I just stopped because inventory is limited and having more items means needing more space.