Hey.. sorry to hear about that..
are you running it from the itch.io app or straight from download? if you're using the itch.io app, try reinstalling Homegirl from it.. I had the same issue with the latest update, but reinstalling seemed to fix it..
if that doesn't work, maybe your config.json file is invalid.. open %APPDATA%\Homegirl\ in explorer and delete/rename config.json and try again..