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Uses two-dimensional "sprites", 2D images created and used on a flat plane, as opposed to the three-dimensional models or environments found in 3D games.

In the style of games made the 8-bit generation of game consoles & computers, or sometimes authentically created to run on original hardware. Common 8-Bit consoles include the Nintendo Entertainment System, Sega Master System, and the Commodore 64

PICO-8 is a fantasy console powered by Lua. Games are distributed as cartridges which double as PNG  images. 

Pixel Art refers to the charming, simplistic, retro/renaissance style of very-low-resolution graphics, such as from the 1977-1995 Atari, GameBoy, & Super Nintendo (SNES) eras.

Sprites are generally 2D images used in games to represent objects. They can be animated or static, and come in different styles like isometric or top-down.