I don’t have the setup to build specifically for macOS on Intel, but I was able to use WineSkin Winery to make an macOS app for it, and it runs with no issues.
I’m using engine WS11WineCX64Bit23.7.1 with wrapper version Wineskin-2.9.2.0. No other changes were needed: only had to copy the extracted zip over.
I’m excited to see something new for Celeste, and I love this!