Just downloaded game and configured Taranis as in the manual. Go into calibration and perform all tasks as asked. At the end when it shows the controls and asks you to move them around, the YAW is backwards. I push the throttle stick to the left, and YAW goes right. Push it to the right and Yaw goes LEFT. Tried in game and the model actually does the same thing. I have tried recalibrating numerous times and it just seems to keep doing this. Other than that, all controls seem to work fine. Controls work fine in the LiftOff (Immersion RC) simulator and all other simulators I have.

Figured it out. If I hold the stick too far to the left, it actually goes into the REVERSE position. If I hold the stick just short of the left side for the YAW, and click OK, the directions are the correct way. Very strange behavior but I am sure it has to do with the offsets and stuff. I have them set by the manual, but maybe there is something strange by my controller. Thanks for all those who viewed the question.

Thanks for reporting back, I think you're right (that it has to do with offset and stuff). Perhaps it can be fixed by tweaking the values a bit (to like 98% instead of 100% or something similar)