I just did a test comparison and when I try to output a PNG Image Sequence, the render takes more than ten times as long. Is there a way to make it faster?

Alternately could there be an option to output a completely uncompressed video? I prefer to handle all of my compression settings in handbrake. 

You can set crf to 0 to uncompress the video. You can also use H265 to improve the quality.

PNG with a large resolution take some time to write because it compress it to use less HD, but i'm working on a option to save it uncompressed.