I was spam-crafting clubs as part of the beginning of a low-level run and happened to get enough intelligence equipment to slam my 10 int up to 20. An unfortunately-fortunate consequence was that I managed to craft a Club that ended up being the artifact Qurasil's Mercy, with full stats and description. To my dismay, it did in fact crash the game upon equipping, and upon reloading, the weapon had lost its description, kept the stats, and kept its crash-inducing behavior (presumably due to this interaction being unintended).
Salvaging it got it out of my inventory, at least, but that's all the testing I did.