This is definitely the most unique Suika-like I've seen, it's great so far!
If you're looking for feedback or ideas, could I suggest adding some kind of 'shop' (maybe every 3-5 battles) where you can trade the witches you've recruited to your polycule to other polycules in exchange for more powerful potions, or different shapes/sizes of beakers? Also, some sort of grimoire of what potions you've encountered and what they do would be cool (though I know you can already just mouse over items to see what they do), and an option to disable text movement would be nice.