There is. Her scene is a one time thing. After that you can't replay it unless you made a save point.
There's a guide for quests on the Discord.
Level up drug making and buy the mortor in one of the shops
During the Save Sakura storyline pick the red fate for Ophelia.
As for the hexanyl you need to level up the skill with gold bars
You can't leave the building until you finish the Save Sakura storyline.
You need to turn it on and off to fill her libido, not fill the 5 eyes.
There's a quest guide on the Discord channel if you need help with anything else.
It's a bug. Can't complete it.
This was fixed in v25.9. It seems you're in v24.8
