So this game is fun, but the difficulty is to high on the outset. I had two easy fixes:
First, make the initial deck only have cards with values from 1 to 3. Whenever you complete a run, add four new cards which are one larger(4 than 5 than 6 etc.). When you add face cards for the first time, add in the jokers as well.
Second, whenever you heal, roll a d6 and add that health to your health. I could also see having the ability to rest between each room.
This is a pretty cool game and I would like to see this expanded upon and refined.