I couldn't open the applications at all
What an elaborate description. What do you mean, you could not open the apps? Literally. What does this mean?
Is there an error message? What do you mean with installing?! 99.9% of all renpy games are unzip and run, there is no "installing". Are you using the itch app? Do you use sandbox mode? What does your taskmanager say about the app status? Is it running, failing silently, hogging ressources, not reacting, and so on. Do you have error files in the game folders. Were the files quarantined by your system.
Also, you are on windows, how do you know your system did not change? For one, there is malware on itch. A lot. Just yesterday I saw things that were sitting around as a time bomb since last year. And then there is windows updates, and those can include drivers.