Hi. Yes, in theory, during the video game club founding quests, you meet Suki and Mayu, and then you can talk to both of them. Have you finished the quests and still can't talk to Mayu? If that is the case, it may be a bug.
Yes, I accepted Yuri's challenge and got to know Suki. I can also talk to her in the room, but after completing the club task, I can only talk to Suki. When I talk to Mayu in the garden, it will show that you don't know this person yet.