Maybe don't think about best experience, think about worst possible experience and how to fix it. Things that could break your game: weird aspect ratio, weird resolution, unexpected or unaccessible control scheme, too quiet/loud sound or sound at all. Make it possible for player with any keyboard/mouse, any speakers/headphones, and any monitor to play your game - then polish it further. Heavy testing and ensuring that your game handles ratio/resolution automatically would work as well. Controls must be very simple or customizable, and volume/mute settings seems mandatory. Good luck!