I am not sure what you mean with the term mainstream. While "indie" is a quality sometimes boasted about, indie games are in general not mainstream.
Itch itself is somewhat obscure. There are games on your list that I knew of, before I even knew, that itch exists, let alone that those games would be sold here.
While not accurate, this list might have at least some "mainstream" games, if you equate steam with mainstream.
https://itch.io/games/steam-key
And as a fun trivia, there a games here on itch that bother to tag indie.