I'm a perma-GM and I usually only play tabletop campaigns in my own homebrew settings. I came across this one, and I loved it so much that I ran a campaign in it. My players loved it so much that I'm now running a second campaign (where they deal with the repercussions of the stuff they did in the first campaign). We're nearing the end of that second campaign, and my players want to know when the third one will start.
This is a thought-provoking setting, with plenty of room for GMs to throw in all kinds of interesting, weird problems for a group to come across - and raise questions of their own.
I love it, is what I'm saying.
For those wondering how "system-agnostic" the setting is: I've run sessions in this setting in Blades In The Dark, Into The Odd, and Cypher, with no changes made to the setting and only minimal changes made to the systems (for example, re-flavoring the Blades factions so they fit in here).