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It can be used in a commercial game. There are links on the page to the licensing page for the details. I'm not sure what exactly you want to know with your second question but the sprites face one side only (two if you flip them) meaning what you see in the preview image is basically what you get.  So it's upto you to make it work for a 2d platformer or a top-down game. 

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Ok, thank you and Christ bless you. For your meditation Matthew 24; get ready, Jesus will return!