I had a lot of fun with this. It's just FUN.
Theme: Not quite sure, I get what you're going for with the inanimate objects becoming animate, not sure it would constitute a weapon as much as just being 'an angry coffee mug'.
Creativity: Love it. This was fun, scratched that 'Portal-esque' mad science itch.
Technical Achievement: You've done well to make this work in only a 48hr jam - I enjoyed the coffee mug attack the most, definitely surprised me when it first happened.
Polish: There was one section with a raised platform that I had to jump up, the enemies couldn't jump down - so I just picked them off from a distance.
Entertainment: Super enjoyable. This was just a fun shooter, and the ammo and health drops were forgiving.
Bonus Points: Easy to load, ran well, looked crisp.
My pet peeves are your choice of font, it didn't really fit the tone of the messages left throughout. Enjoyed the ending (left me wondering what happened after the final objective...)