RPG Maker has very strict requirements for things like tile size, sheet size, and autotile construction. This will work fine with any engine that doesn't impose strict limitations. Unity and Godot are popular in the Mana Seed Discord.
If you really want to use this with RPG Maker, you need to research the requirements of your version, and how to import custom assets. You can make this work by editing it yourself, just understand that RPG autotile brushes will never work with any of my tilesets.