As someone who struggles with having to send sometimes contradictory signals to my hands in a twin-stick shooter (e.g. left hand up, right hand down/left) I have just learned than an auto-battling Binding of Isaac is what I need! Can't play Isaac because I can't do the twin stick thing.
Satisfying feel and weight to everything. I like that as a long time subscriber I can tell you made the hurt noise with your own voice but that may be good or bad from your point of view.
It seems like enemies can get stuck on scenery (trying to move directly toward player "through" a wall and therefore just pressing their face into the wall with no effect) - the slimes seem particularly prone to this, didn't notice it with others but would assume snakes or other non-flying types might have a similar issue if their pathfinding is based on the same principles.
I was able to complete the demo after buying two permanent damage upgrades and one health upgrade although didn't really need the health. Not sure if that is useful to you or not. I think it was five attempts to get there.
Overall I liked it, found it had that "just one more go..." quality to it and like I say an Isaac auto-battler is apparently what I needed to be able to play this sort of game so while some might dislike that, I can tell you there's people who will eat it up.