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In the bad path, they never got around to viewing Nano as a friend or family member, but merely as a tool to complete their assignment. 
This is why Lycoris uses Nano's dependency on him to boost his own ego, why Oleander didn't bother properly explaining to Nano how bodies work and made it figure things out on its own, and why Strelitzia didn't respect its boundaries or bodily autonomy. So yes, the irony was definitely intentional. :D