Notes as I play:
Visual improvements are nice, it's getting there.
Maybe it's just RNG, but I feel like it's more likely for me to get decent slot combos. Makes the pace of combat faster. Suppose it could also be how the default cards are buffed. Poison is a nice addition, allowing for some chip damage if you don't get another combo. Having the slots be automatic after the first input is better I think, less mashing involved.
I ended up leaning into a poison build, getting the Dubious Drink. I also got the Horseshoe, which feels almost OP given how it means you never have a turn of doing nothing. It was still relatively close, but I finally managed to beat that green rat of a leprechaun after 3 DDs(not that I was trying too hard).
Did another run, going into a red and yellow build. Found a gift shop, which is a fun addition. It was especially useful for getting rid of a tourist photo. It was fun, but as to be expected a money build would be hard pressed to best the boss. The game over screen is a lot nicer, though I will mention the text on the bottom spills over onto the red outline a little. Specifically the first letter P.