Really nicely done! I like using the vignette effect and the greyscale to affect the atmosphere and how you also used it on the title screen, which I didn't notice until I started to write this. :) I wasn't expecting the power ups I chose to have that consequence for the boss, I really regretted the imaginary friend choice!! :D
I also liked the emoji expressing the Jacob's emotions in the cutscenes, it was a cute touch when dealing with a dark narrative. I've played quite a few games similar to the roguelike gameplay and I think this is the first one where the enemies move in more erratic patterns, it caught me off guard in a good way, normally those types of games are a bit more casual to play and I had to really work to succeed.