I like the use of the theme and that you're "unbuilding" the city. The controls are clear, but I would have liked a button to advance the intro text. Its good that you show the timer for the intro text advancing though. The music is good but it was loud for me initially and there isn't an in-game volume setting. It was cool to figure out where the buildings creating bad effects are and finding the special building patterns. Also the changing layout adds a layer of unpredictability to the game. It wasn't very clear why the game ended. I assume its because the population decreased too much, but I had 50 left so I thought then that wasn't the problem.
I got 21200 pts the 2nd time I won. Let's see if someone can do better. :)