Great stuff man, love it. I've been playing MtG and roguelikes for like 20 years, so this is perfect for me. Your UI work is top notch. I really need to crib some notes from you on making a satisfying UI. The card art looks great, very nice use of AI. I've thought for a while that a card game would be a good candidate for such a thing, because you don't need, or even want, perfect coherence with each piece.
I have a display issue. My monitor is 1920x1200 by default, and that causes the left and right side of the screen to clip. I know monitor resolution stuff is a huge pain in the ass, but you might want to sort that out. In my last game, I got dinged so many times in reviews because I didn't handle different resolutions very well.
Overall, it's an excellent fusion of slay the spire and MtG, both games I really love. You've got something really nice here, it's fun and very well polished. Just get your Steam page up hahah.