I played the game up until the end of Murphy, and then quit. I tried to reload today (using same user name), and it tells me a new game will be started. I checked the save directory, and it has a file called loginDesktop.ini, and one called PPC.sav. Neither file has much info in them, and there is no mention of my saved character.

I'm running Windows 10.

Any idea what happened?

same here, use admin to create a save file but never save after complete a few cases