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Oh no??? Do you mean that you played it once, and then tried to play it again and it suddenly doesn't work? That seems very odd... ðŸ¤” It's hard for me to know exactly what's going on. What OS are you using? You could perhaps try to change to the 32-bit version if you can't play the 64-bit version? (or the other way around) Are you able to play other games made with Ren'Py? If you can't play any Ren'Py games, it could potentially be something with your driver... but I'm unsure. I was trying to find some solutions online but its hard to know more since I don't know exactly your situation. There are other hits in Google for instance with ppl talking about not being able to start up Ren'Py games, for instance, and some suggestions have included updating graphics drivers or changing the renderer used to display the Ren'Py games.