Minor bug report: if you click through the confirmation prompt for rerolling too fast it will give you the powerup and lock your mouse inputs until either the next level up or you lose (only tested with mouse, not sure if it happens on pad)
I'm only able to consistently make it happen with some kind of unnaturally fast clicking method (for example mouse keys, an autoclicker would probably do it too) but I have had it happen several times both by accident and on purpose just with normal mouse clicking, like if I accidentally double click it too fast.