itch.io

Oh sorry, I missed your previous comment. That looks like a permissions error I've seen before, though it is usually only present when trying to open the game on a Mac. My first two suggestions would be to run the game as administrator, or move it to your desktop and try running it. It could be that the filepath is too long to read, in which case you'll have to shorten the name of the folder(s) that the game is contained within. If those don't work, check through right click -> properties -> security that both the game and the game's folder have read/write permissions.