Are you trying to install through the Itch App or are you downloading the full APK and installing it manually? If it's the latter, then:
1. Make sure you have at least 5GB+ storage space free (Android needs about 4-5x as much free space as apps require to install them)
2. DO NOT delete the previous version! Install on top of it
3. Use SplitAPK installer ( https://play.google.com/store/apps/details?id=com.aefyr.sai&hl=en_GB&gl=US ) which gives a higher chance of success and - on failure - a much more useful error log.
If you're trying to install via the Itch App then that's an Itch issue and unfortunately you'll have to get in touch with their support team, sorry!