Weapon suggestion: Golden gauntlet. 5-10 strength damage. Can be found in the starting lab but requires very high (80+) senses to find the container (its well hidden) and very high Knowledge / Intelligence (80+) to open the box (locked with a puzzle lock). Looks like a normal clothing glove but colored gold. Special effect is a 1% chance to deal a super crit (actual: 999 physical damage with no bonus from stats or other equipment) but only if its the only equipped weapon. Unique item - only one can be found per play through.
Most of the time the item is just a trophy item for high level characters but has a 1% chance to deal a super powerful hit to most NPC's in combat (If not immune to physical damage, The attack is not prevented from hitting, NPC has an active damage reflection ability as examples of what could have a negative effect - Yes, its powerful but not without limitations).