Threw in the towel during the section where you have to gather the levers while being chased. I found a set of numbers that I'm assuming made up the combination to the safe in one of the rooms, but there was one strange symbol mixed in that made no sense. Was it supposed to be a mystery number? If that's the case, I wasn't going to play that part repeatedly to find out. You get about one crack at entering the combination, even if you evade the killer. Somehow he always knows you're in that room. Might want to give that a look, too.
Also, that section with the "combat" is absolutely brutal. I have a feeling most players probably would've called it quits at that point. I finally figured out that the enemies running towards you need to be clicked on at just the right time, so you don't even see the object you're swinging at them make it into the frame. Very unintuitive and nonsensical.
I'm not trying to be overly harsh, but I put several hours into this trying to make it through and just couldn't do anymore. I think you have the makings of a decent game here, but it definitely needs some wrinkles ironed out.