Hello! :)
Thank you for your comment!
Usually this happens when some data is missing/incompatible/corrupted. A re-download might fix it, since sometimes the downloads can be a bit unstable on itchio! (If there are no conflicts with other programs such an anti-viruses etc.)
Otherwise, make sure you're not using any old save data on a newer version of the game or anything else like that.
It is quite the rare problem from what we saw (only reported twice and it's the first time we hear about it for our game), but hopefully we can find a solution! :)