When accepting protection from the witch against the Nameless, will it prevent future interactions with Nameless later on? I like his character so far and I don't want to miss out on content
Other than small differences in the interactions between you and Nameless and the fact that if you don't want the protection you don't receive the amulet of strong mind, there are not visible differences. Although I think that you can get more hidden likes if you don't accept protection, but this is my theory.